Emerging HIFU Applications in Cancer Therapy
In the following
Over the last 10 years a growing number of clinical trials have examined HIFU treatment of both malignant and benign
For some of these emerging indications or signs, HIFU is poised to become a serious adjunct or alternative to current standard treatments – including surgery, gene therapy, immunotherapy, radiation, and chemotherapy.
Current or nowadays commercially available HIFU devices are marketed for their applications of thermal ablation. Whereas, in the future, lower energy treatments may play a significant or important role in mediating targeted drug and gene delivery for cancer treatment.
Conclusion and Future Application
High intensity focused ultrasound or HIFU is a non-invasive and effective technique to achieve tumor ablation and to facilitate targeted medical therapy to tumors. Even though HIFU technology has been in clinical use since the 1950s, limited complimentary technologies have hindered or obstructed its advancement into clinical oncology beyond a small spectrum of disease.
HIFU or High intensity focused ultrasound is poised to bridge the promising data from preliminary trials to more robust and randomized clinical trials for treatment of liver, kidney, bone, breast, pancreatic, thyroid, desmoid, parathyroid and brain tumors.
Even though completion of such trials is time-consuming and challenging for relatively uncommon diseases, the results will help to better define the emergent role of HIFU in management of a broad and wide spectrum of oncology.